• Treatment

    Early Results for Gene-Silencing Huntington’s Drug ‘Exceed Expectations’

    By Kendall K. Morgan · January 15, 2018 ·

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    Last month, Ionis Pharmaceuticals announced the long-awaited results of a clinical trial designed to test the safety and tolerability of a gene-silencing drug called IONIS-HTTRx… Continue Reading »

  • Column

    Genome Culture: Ohio Passes Law Banning Abortion Because of Down Syndrome

    By Laura Hercher · January 11, 2018 ·

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    Last month in Ohio, a bill was signed into law that, as of March 1, makes it a felony to perform an abortion on a… Continue Reading »

  • Treatment

    Personalized Insulin Pumps Help Patients With Type 1 Diabetes

    By Audrey Carson · January 5, 2018 ·

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    Managing type 1 diabetes is a full-time job, one that bears an unrelenting reminder of the chronic disease through daily injections and pinpricks. But a… Continue Reading »

  • Research

    A Modified CRISPR Tool Creates New Treatments for Diseases

    By Kelsey Kennedy · December 29, 2017 ·

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    Instead of making permanent gene modifications with a common DNA editing tool, researchers can now make temporary changes thanks to some clever modifications. Scientists at… Continue Reading »

  • Policy

    In a Heartbeat: Mandatory Screening Saves Infant Lives

    By Lauren Arcuri · December 22, 2017 ·

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    A new study published in the Journal of the American Medical Association confirms that screening of critical congenital heart disease (CCHD) using a simple test… Continue Reading »

  • Column

    Genome Culture: Genetics Fulfills Some Old Promises in 2017

    By Laura Hercher · December 21, 2017 ·

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    For decades, genetics has been the science that cried wolf. Stem cell therapies were going to regenerate our aging body parts in the 1980s. Gene… Continue Reading »

  • Innovation

    The Wild West of Vaginal Microbiome Testing

    By Heather Millar · December 18, 2017 ·

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    I’m sitting with about a dozen other women around a table in a biotech startup office south of Market Street in San Francisco, California. We’re… Continue Reading »

  • Research

    A Head Start on Predicting Concussion Symptoms in Kids

    By Dyani Sabin · December 14, 2017 ·

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    Most of the time, a concussion comes with a headache that might last a few days. But sometimes the resulting headaches, dizziness, and sleep issues… Continue Reading »

  • Column

    Genome Culture: How to Decide Which DNA Tests to Buy

    By Laura Hercher · December 7, 2017 ·

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    ‘Tis the season for aggressive marketing campaigns, and my inbox is littered with ads from HomeDNA, a company I’d never heard of until it started… Continue Reading »

  • Policy

    Insuring Costly Orphan Drugs

    By Sonya Collins · December 6, 2017 ·

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    Last month, health insurer Anthem, owner of Blue Cross and Blue Shield, announced that, under certain circumstances, it would cover the Duchenne muscular dystrophy drug… Continue Reading »

  • Genetics

    A Comprehensive Cancer Gene Test Gets the Go-Ahead

    By Knvul Sheikh · December 4, 2017 ·

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    A test that can quickly detect cancer-causing mutations in 324 genes has gained approval from the Food and Drug Administration (FDA) and a green light… Continue Reading »

  • Technology

    A High-Tech Pill to Swallow

    By Greg Uyeno · December 1, 2017 ·

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    We live in an age of smartphones. Their rise in popularity and accessibility has been accompanied by criticism that they serve as constant distractions, upset… Continue Reading »

  • Treatment

    Seeing Into the Future

    By Lauren Arcuri · November 30, 2017 ·

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    Spark Therapeutic’s experimental treatment for a hereditary form of blindness called Leber congenital amaurosis (LCA) is close to being available to patients. An advisory committee… Continue Reading »

  • Column

    Genome Culture: Welcoming in a New Era of Direct-to-Consumer Genetic Testing

    By Laura Hercher · November 24, 2017 ·

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    For years, entrepreneurs have envisioned an industry based on direct-to-consumer genetic testing for the science-curious, the worried well, the fitbit wearers. They’ve watched the cost… Continue Reading »

  • Treatment

    Big Data Meets Big Doo-doo

    By Greg Uyeno · November 21, 2017 ·

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    In 2008, Rhode Island gastroenterologist Colleen Kelly diagnosed a patient with a Clostridium difficile bacterial infection. The infection alters the composition of the community of… Continue Reading »

  • Innovation

    First Person Receives Gene Editing in the Body

    By Knvul Sheikh · November 16, 2017 ·

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    On Monday, November 13, Brian Madeux became the first patient to receive an experimental therapy designed to alter his DNA. The 44-year-old has a rare… Continue Reading »

  • Column

    Extreme Parenting

    By Kasey Edwards · November 16, 2017 ·

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    Almost all parents can relate to the intense and sometimes overwhelming compulsion to protect their children. Some parents focus on providing their children with the… Continue Reading »

  • Innovation

    A Brand-New Class of RNAi Drugs Breaks Through

    By Heather Millar · November 14, 2017 ·

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    Rare diseases affect about 25 to 30 million Americans. There are more than 6,800 rare disorders, and the vast majority of them don’t have treatments…. Continue Reading »

  • Research

    China Joins the Personal Genome Project

    By Sonya Collins · November 13, 2017 ·

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    The Personal Genome Project (PGP) has expanded its global network to China. PGP China teams up with PGPs in the U.S., Canada, the U.K., and… Continue Reading »

  • Policy

    FDA Ruling Makes Direct-to-Consumer Genetic Tests More Accessible

    By Kelsey Kennedy · November 10, 2017 ·

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    Consumers are likely to see more genetic health risk tests on the market due to a new approval system announced by the Food and Drug… Continue Reading »

  • Column

    Genome Culture: When Genetics’ Race Problem Rears Its Ugly Head

    By Laura Hercher · November 9, 2017 ·

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    It may seem like a long time since white supremacists marched in the streets of Charlottesville. It may seem like decades must have passed, because… Continue Reading »

  • Research

    Sex Cells: More Mutations May Come from Dad than Mom

    By Greg Uyeno · November 3, 2017 ·

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    Age is, unfortunately, more than just a number. Prospective parents know this. Age is linked to declining fertility in both men and women, as well… Continue Reading »

  • Profiles

    Meet the Communications Specialist Fighting to Change Prescription Drug Pricing

    By Sonya Collins · November 2, 2017 ·

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    As a 40-year veteran communications specialist in health policy, David Mitchell of Potomac, Maryland, knew all the health campaigns by heart. “Campaign for Tobacco-Free Kids,… Continue Reading »

  • Treatment

    FDA Says Yes to Yescarta

    By Knvul Sheikh · October 27, 2017 ·

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    On October 18, the Food and Drug Administration approved a second groundbreaking drug that uses patients’ own genetically modified immune cells to attack cancer. The… Continue Reading »

  • Research

    Of Gut Microbes, Jet Lag, and Weight Gain

    By Kendall K. Morgan · October 27, 2017 ·

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    Microbes living in the guts of both people and animals can make all the difference when we (or they) step on the scale. “If you… Continue Reading »